We reconstructed cellular motility in vitro from individual proteins to investigate how actin filaments are organized at the leading edge.Using total internal reflection fluorescence microscopy of actin filaments, we tested how profilin, Arp2/3, and capping protein (CP) function together to propel thin glass nanofibers or beads coated with N-WASP W
Summary: Morphological plasticity is a key virulence trait for many fungal pathogens.For the opportunistic fungal pathogen Candida albicans, transitions among yeast, pseudohyphal, and hyphal forms are critical for Quickstrikes virulence, because the morphotypes play distinct roles in the infection process.C.albicans morphogenesis is induced in resp
Gliomas with chromosome 1p/19q codeletion were considered a specific tumor entity.This study was designed to reveal the biological function alterations tightly associated with 1p/19q codeletion in gliomas.Clinicopathological and RNA sequencing data from glioma patients were obtained from The Cancer Genome Atlas and Chinese Glioma Genome Atlas datab
The regulation of the Glucocorticoid Receptor (GR) transcript was investigated in the gills of Atlantic salmon (Salmo salar) during the parr-smolt transformation.Sampling of parr and smolt fish was performed between December and July and in particular during the smoltification period occurring in spring.Quantification of GR transcripts revealed dif
Temporary Tattoo Simulation studies show that jump performance can be improved by increasing the depth of countermovement.The purpose of this study was to determine how modifications to the depth of countermovement lead to changes in jump height and the biomechanical parameters related to center of mass displacement and force application.Twenty-nin